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In an effort to prevent family history from repeating itself, meddlesome mom Daphne Wilder (Diane Keaton) attempts to set up her youngest daughter, Milly (Mandy Moore), with Mr. Right. Meanwhile, her other daughters (Lauren Graham and Piper Perabo) try to keep their mom's good intentions under control. Tom Everett Scott, Colin Ferguson and Gabriel Macht also star in director Michael Lehmann's multigenerational mother-daughter comedy.